Clostridia VS Streptococcus thermophilus
Chelation, 一個多月.間中因為blood test還有你生病,停了兩個星期.療程幾乎不怎麼順利.而這段期間,你的streotypy behaviours 又回來了.媽媽頭痛!!!
媽媽懷疑你腸道菌群又不平衡了.
[extract: Gut and Psychology Syndrome (GAPS) By Dr. N. Campbell-McBrige]
source: http://www.gaps.me/?page_id=20
So, what kind of toxins are we talking about?
There are many toxins, which we have not studied very well yet. But some toxins have received a considerable amount of research. Let us have a look at them.
Acetaldehyde & AlcoholThe most common pathogenic microbes shown to overgrow in the digestive systems of children and adults with neuro-psychiatric conditions are yeasts, particularly Candida species. Yeasts ferment dietary carbohydrates with production of alcohol and its by-product acetaldehyde. Let us see what does a constant exposure to alcohol and acetaldehyde do to the body.
Liver damage with reduced ability to detoxify drugs, pollutants and other toxins.
Pancreas degeneration with reduced ability to produce pancreatic enzymes, which would impair digestion.
Reduced ability of the stomach wall to produce stomach acid.
Damage to immune system.
Brain damage with lack of self-control, impaired co-ordination, impaired speech development, aggression, mental retardation, loss of memory and stupor.
Peripheral nerve damage with altered senses and muscle weakness.
Direct muscle tissue damage with altered ability to contract and relax and muscle weakness.
Nutritional deficiencies from damaging effect on digestion and absorption of most vitamins, minerals and amino acids. Deficiencies in B and A vitamins are particularly common.
Alcohol has an ability to enhance toxicity of most common drugs, pollutants and other toxins.
Alteration of metabolism of proteins, carbohydrates and lipids in the body.
Inability of the liver to dispose of old neurotransmitters, hormones and other by-products of normal metabolism. As a result these substances accumulate in the body, causing behavioural abnormalities and many other problems.
Acetaldehyde is considered to be the most toxic of alcohol by-products. It is the chemical, which gives us the feeling of hangover. Anybody who experienced a hangover would tell you how dreadful he or she felt. Children, who acquire abnormal gut flora with a lot of yeast from the start, may never know any other feeling. Acetaldehyde has a large variety of toxic influences on the body. One of the most devastating influences of this chemical is its ability to alter the structure of proteins. Acetaldehyde – altered proteins are thought to be responsible for many autoimmune reactions. Children and adults with neuro-psychiatric problems are commonly found to have antibodies against their own tissues.
Clostridia NeurotoxinsThere are about 100 different Clostridia species known so far. They are present in the stools of people with autism, schizophrenia, psychosis, severe depression, muscle paralysis and muscle tonus abnormalities and some other neurological and psychiatric conditions. Many Clostridia species are normal inhabitants of a human gut. For example Clostridium tetani is routinely found in the gut of healthy humans and animals. Everybody knows that tetanus is a deadly disease, due to an extremely powerful neurotoxin Clostridium tetani produces. Clostridium tetani, which lives in the gut, is normally controlled by the beneficial bacteria and does us no harm, because its toxin cannot get through the healthy gut wall. Unfortunately, patients, which we are talking about, do not have a healthy gut wall. In gut dysbiosis this powerful neurotoxin can get through the damaged gut lining and then cross the blood-brain barrier affecting the person’s mental development. Many other species of Clostridia (perfringens, novyi, septicum, histolyticum, sordelli, aerofoetidum, tertium, sporogenes, etc) produce toxins similar to tetanus toxin as well as many other toxins. Dr. William Shaw at Great Plains Laboratories describes in detail number of autistic children, who showed serious improvements in their development and biochemical tests while on anti-Clostridia medication. Unfortunately, as soon as the medication was stopped the children slipped back into autism, because these children do not have healthy gut flora to control Clostridia and not to allow their toxins through the gut lining into the bloodstream. In many cases Clostridia were not identified in the stools of these children, because Clostridia are strict anaerobes and are very difficult to study. We need to come up with some better ways of testing for these potent pathogens.
Yeasts and Clostridia have been given a special opportunity by the era of antibiotics. Broad-spectrum antibiotics do not touch them while killing the beneficial bacteria in the gut, which are supposed to control the yeasts and Clostridia. So, after every course of antibiotics these two pathogenic groups get out of control and overgrow. The patients that we are talking about usually are exposed to numerous courses of antibiotics pretty much from the beginning of their lives.
Gluteomorphins & Casomorphins or opiates from gluten and casein.Gluten is a protein present in grains, mainly wheat, rye, oats, barley. Casein is a milk protein, present in cow, goat, sheep, human and all other milk and milk products. In the bodies of children and adults with autism and schizophrenia these proteins do not get digested properly due to the fact that their digestive systems are full of abnormal microbial flora and hence unhealthy. As a result of misdigestion gluten and casein turn into substances with similar chemical structure of opiates, like morphine and heroin. There has been quite a substantial amount of research done in this area by Dohan, Reichelt, Shattock, Cade and others, where gluten and casein peptides, called gluteomorphins and casomorphins, were detected in the urine of schizophrenic patients and autistic children. Incidentally, these substances were also found in patients with depression and rheumatoid arthritis. These opiates from wheat and milk get through the blood-brain barrier and block certain areas of the brain, just like morphine or heroin would do, causing various neurological and psychiatric symptoms. Based on this research the gluten and casein free diet (GFCF diet) has been developed.
Dermorphin & Deltorphin
These are two frightening toxic substances with opiate structure, which have been found in autistic children by a biochemist Alan Friedman, PhD. Dermorphin and deltorphin were first identified on the skin of a poison dart frog in South America. Native people used to dip their darts into the mucous on these frogs in order to paralyse their enemy, because deltorphin and dermorphin are extremely potent neurotoxins. Dr Friedman believes that it is not the frog that produces these neurotoxins, but a fungus, which grows on the skin of this frog. It is possible that this fungus grows in the gut of autistic children, supplying their bodies with dermorphin and deltorphin.
爸爸今午就媽媽傳來這個
"...often times probiotics, can have a bacteria in them called streptococcus thermophilus which is a natural bacteria that is a beneficial bacteria that is supposed to improve digestion and overall health. Some yogurts also contain streptococcus thermophilus. Theoretically streptococcus thermophilus is very different in protein structure than Group A Beta Hemolytic Strep and therefore should not be impacting the manifestations of PANDAS like obsessive compulsive disorder. However the problem is that in my own clinical practice I have not seen this to be true. Many children I see, whether they are on the Autism spectrum or not, do not seem to react well to probiotics with streptococcus thermophilus if they have PANDAS."
全文在這裡,Dr Kurt's "Pandas, Probiotics Problems and Autism" -
http://www.autismrecoverytreatment.com/autism-treatment-%e2%80%93-pandas-probiotic-problems-and-autism/
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